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Review
. 2000:924:1-7.
doi: 10.1111/j.1749-6632.2000.tb05552.x.

Genetic factors in the genesis of Alzheimer's disease

P H St George-Hyslop  1
Affiliations
Review

Genetic factors in the genesis of Alzheimer's disease

P H St George-Hyslop. Ann N Y Acad Sci. 2000.

Abstract

At least four different genes have been identified that are associated with inherited susceptibiltiy to Alzheimer's disease. Some of the genes are highly penetrant (PS1, PS2, beta APP); the other, APOE, is a weaker susceptibility factor. Several additional genes are suspected to exist but have not yet been cloned.

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