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Multicenter Study
. 2000 Dec;125(10):948-53.
doi: 10.1016/s0003-3944(00)00402-8.

[Assessment of quality of life after antireflux surgery]

[Article in French]
P Hauters  1 , J Sorrentino, M Papillon, H Johanet, R Janer, S Auvray, O Merlier, J Saba, C Bertrand, D Poels, C Peillon
Affiliations
Multicenter Study

[Assessment of quality of life after antireflux surgery]

[Article in French]
P Hauters et al. Ann Chir. 2000 Dec.

Abstract

Aim of the study: To assess the quality of life (QoL) of patients operated for gastroesophageal reflux disease (GERD).

Patients and methods: This prospective study included 82 consecutive patients submitted to antireflux surgery between October 1998 and January 1999. A new questionnaire was used to assess their QoL: the Gastrointestinal Quality of Life Index (GIQLI) that includes 36 items concerning 5 dimensions: symptoms, vitality, emotions, social relations and medical treatment. The series consisted of 44 men and 38 women with a mean age of 47 years (range: 18-78). QoL was assessed before and 6 months after surgery; the follow-up rate was 94% (77/82). The pre- and postoperative GIQLI scores of the study group and the GIQLY score of a control group of 110 healthy patients were compared.

Results: Before surgery, the GIQLI score (90 +/- 23) was greatly impaired compared to the score (123 +/- 13) observed in the control group (p < 0.001). After surgery, the GIQLI score (110 +/- 23) increased significantly (p < 0.001), but remained statistically lower than the score of the control group (p < 0.001). The postoperative score recorded in the symptoms dimension was lower than the control group score: 55 +/- 11 versus 66 +/- 6 (p < 0.001), while no significant difference was observed in the other 4 dimensions. Univariate statistical analysis revealed that the postoperative GIQLI score (y) was correlated with the preoperative GIQLI score (x) according to the formula: y = 0.43 x + 71 (p < 0.001) and the sex of the patients, as the postoperative GIQLI score was higher in male patients (115 +/- 19) than in female patients (103 +/- 23) (p < 0.02).

Conclusion: The QoL of the patients was greatly improved after antireflux surgery, but remained lower than that of a control group of healthy subjects. Better patient selection should improve the results. In our series, male patients or patients with a high preoperative GIQLI score were the best candidates for antireflux surgery.

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