doi: 10.1016/s0140-6736(00)03573-x.
Multidrug-resistance protein 1 in focal cortical dysplasia
- PMID: 11197364
- DOI: 10.1016/s0140-6736(00)03573-x
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Multidrug-resistance protein 1 in focal cortical dysplasia
Lancet.
.
Abstract
Drug resistance in epilepsy is poorly understood. We used routine immunohistochemistry to assess overexpression of a multidrug-resistance protein in dysplastic neurons, glia, and around vessels in surgically resected epileptogenic human brain tissue. We showed non-tumoral overexpression of this multidrug-resistance protein, which might contribute to drug resistance in epilepsy caused by focal cortical dysplasia.
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