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. 2001 Jan;103(1):52-9.
doi: 10.1034/j.1600-0447.2001.00147.x.

Quality of Life (QOL) of patients with Gilles de la Tourette's syndrome

K Elstner  1 , C E Selai, M R Trimble, M M Robertson
Affiliations

Quality of Life (QOL) of patients with Gilles de la Tourette's syndrome

K Elstner et al. Acta Psychiatr Scand. 2001 Jan.

Abstract

Objective: This is the first study to investigate the Quality of Life (QOL) of patients with Gilles de la Tourette's Syndrome (GTS).

Method: One hundred and three out-patients with GTS completed a semi-structured interview and 90 of these completed questionnaires screening for depression, anxiety and obsessive-compulsive behaviour. QOL was measured with the SF-36 and the Quality of Life Assessment Schedule (QOLAS).

Results: Patients with GTS showed significantly worse QOL than a general population sample. They had better QOL than patients with intractable epilepsy as measured by the QOLAS, although the SF-36 showed significant differences on the subscales Role Limitation due to physical problems and Social Functioning only. Factors influencing QOL domains were employment status, tic severity, obsessive-compulsive behaviour, anxiety and depression.

Conclusion: QOL is impaired in patients with GTS. Measurement of QOL could be used alongside conventional measurements to assess benefit of treatment. We recommend the QOLAS and SF-36 be used.

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