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. 1975 Jan 4;1(5948):12-4.
doi: 10.1136/bmj.1.5948.12-a.

I alpha-hydroxycholecalciferol: a treatment of renal bone disease

I alpha-hydroxycholecalciferol: a treatment of renal bone disease

G R Catto et al. Br Med J. .

Abstract

Three patients with chronic renal failure on maintenance haemodialysis have been treated with 1 alpha-hydroxycholecalciferol (1 alpha-OHCC), a synthetic vitamin D analogue. A daily dose of 2 mug by mouth produced a significant increase in both calcium absorption from the gastrointestinal tract and calcium content of bone. Treatment with 1 alpha-OHCC appears to be effective in cases of metabolic bone disease associated with chronic renal failure.

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