Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2000:(60):125-37.
doi: 10.1007/978-3-7091-6301-6_8.

Monitoring neuroprotection and restorative therapies in Parkinson's disease with PET

D J Brooks  1
Affiliations
Review

Monitoring neuroprotection and restorative therapies in Parkinson's disease with PET

D J Brooks. J Neural Transm Suppl. 2000.

Abstract

In this article the role of functional imaging (PET and SPECT) as a surrogate marker for following the progression of Parkinson's disease (PD) is discussed. The potential value of PET and SPECT for assessing the efficacy of putative neuroprotective agents in PD is considered and a review of 18F-dopa PET findings in transplantation trials involving implantation of human and procine fetal mesencephalic tissue is presented. It is concluded that functional imaging provides a valuable adjunct to clinical assessment when judging the efficacy of neuroprotective and restorative approaches to PD.

PubMed Disclaimer

MeSH terms

Substances

LinkOut - more resources