Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2001 Feb;107(2):393-7.
doi: 10.1097/00006534-200102000-00014.

Do not use epinephrine in digital blocks: myth or truth?

Affiliations
Clinical Trial

Do not use epinephrine in digital blocks: myth or truth?

B J Wilhelmi et al. Plast Reconstr Surg. 2001 Feb.

Abstract

The purpose of this study was to examine the role for epinephrine augmentation of digital block anesthesia by safely prolonging its duration of action and providing a temporary hemostatic effect. After obtaining approval from the review board of the authors' institution, 60 digital block procedures were performed in a prospective randomized double-blinded study. The digital blocks were performed using the dorsal approach. All anesthetics were delivered to treat either posttraumatic injuries or elective conditions. Of the 60 digital block procedures, 31 were randomized to lidocaine with epinephrine and 29 to plain lidocaine. Of the procedures performed using lidocaine with epinephrine, one patient required an additional injection versus five of the patients who were given plain lidocaine (p = 0.098). The need for control of bleeding required digital tourniquet use in 20 of 29 block procedures with plain lidocaine and in 9 of 31 procedures using lidocaine with epinephrine (p < 0.002). Two patients experienced complications after plain lidocaine blocks, while no complications occurred after lidocaine with epinephrine blocks (p = 0.23). By prolonging lidocaine's duration of action, epinephrine may prevent the need for an additional injection and prolong post-procedure pain relief. This study demonstrated that the temporary hemostatic effect of epinephrine decreased the need for, and thus the potential risk of, using a digital tourniquet (p < 0.002). As the temporary vasoconstrictor effect is reversible, the threat of complication from vasoconstrictor-induced ischemia is theoretical.

PubMed Disclaimer

Comment in

  • Epinephrine-induced digital ischemia relieved by phentolamine.
    Khairalla E. Khairalla E. Plast Reconstr Surg. 2001 Nov;108(6):1831-2. doi: 10.1097/00006534-200111000-00084. Plast Reconstr Surg. 2001. PMID: 11711987 No abstract available.
  • Epinephrine in the finger.
    Wilhelmi BJ, Blackwell SJ. Wilhelmi BJ, et al. Plast Reconstr Surg. 2002 Sep 1;110(3):999; author reply 999-1000. Plast Reconstr Surg. 2002. PMID: 12172185 No abstract available.
  • Digital blocks with or without epinephrine.
    Andrades PR, Olguin FA, Calderón W. Andrades PR, et al. Plast Reconstr Surg. 2003 Apr 15;111(5):1769-70. doi: 10.1097/00006534-200304150-00040. Plast Reconstr Surg. 2003. PMID: 12655238 Clinical Trial. No abstract available.

LinkOut - more resources