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. 1975 May;35(5):1293-5.
doi: 10.1002/1097-0142(197505)35:5<1293::aid-cncr2820350504>3.0.co;2-w.

Anaplastic giant-cell carcinoma of the thyroid. A study of treatment and prognosis

B Jereb, J Stjernswärd, T Löwhagen

Anaplastic giant-cell carcinoma of the thyroid. A study of treatment and prognosis

B Jereb et al. Cancer. 1975 May.

Abstract

In 79 cases of histologically verified anaplastic giant-cell carcinoma, symptoms, treatment, and prognosis were documented. Seventy-eight patients are dead, the mean survival time being 2.5 months. One patient is cured. It was concluded that surgery and/or radiotherapy alone are not sufficient. The results from an additional 8 patients also treated with methotrexate indicate a positive therapeutic effect, the mean survival time being 9.4 months. Disappearance of recurrent tumor or pulmonary metastases was noted in 2 patients.

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