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Editorial
. 2001 Feb 27;98(5):2122-4.
doi: 10.1073/pnas.061024098.

PEDF: Raising both hopes and questions in controlling angiogenesis

Editorial

PEDF: Raising both hopes and questions in controlling angiogenesis

G J Chader. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Effect of PEDF on retinoblastoma morphology. (A) Proliferating, undifferentiated Y-79 retinoblastoma cells in culture. (B) Nonproliferating cells treated with PEDF demonstrating neuronal-like morphology. [Reproduced with permission from ref. (Copyright 1994, Academic Press).]
Figure 2
Figure 2
In situ angiogenesis in PEDF-treated retinas. Low-power (Left) and high-power (Right) views of retinas of mice exposed to hyperoxia and subsequently treated with vehicle (ad), or with PEDF at 11.2 (e and f) or 22.4 (g and h) μg/day.

Comment on

References

    1. Stellmach V, Crawford S, Zhou W, Bouck N. Proc Natl Acad Sci USA. 2001;98:2593–2597. . (First Published January 23, 2001; 10.1073/pnas.031252398) - PMC - PubMed
    1. Dawson D, Volpert O, Gillis P, Crawford S, Xu H-J, Benedict W, Bouck N. Science. 1999;285:245–248. - PubMed
    1. Tombran-Tink J, Johnson L. Invest Ophthalmol Visual Sci. 1989;30:1700–1709. - PubMed
    1. Tombran-Tink J, Chader G, Johnson L. Exp Eye Res. 1991;53:411–414. - PubMed
    1. Steele F, Chader G, Johnson L, Tombran-Tink J. Proc Natl Acad Sci USA. 1992;90:1526–1530. - PMC - PubMed

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