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Review
. 2001 Jan;3(1):11-21.
doi: 10.1016/s1286-4579(00)01352-6.

Orientia tsutsugamushi infection: overview and immune responses

S Y Seong  1 , M S Choi, I S Kim
Affiliations
Free article
Review

Orientia tsutsugamushi infection: overview and immune responses

S Y Seong et al. Microbes Infect. 2001 Jan.
Free article

Abstract

Orientia tsutsugamushi, an obligate intracellular bacterium, was isolated for the first time in 1930. Infections by virulent strains are characterized by fever, rash, eschar, pneumonia, myocarditis, and disseminated intravascular coagulation. Here we review the general aspects of O. tsutsugamushi and immune responses in terms of inflammation, protective immune mechanisms, and immunogenic antigens.

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