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Review
. 2001 Mar 1:6:D388-405.
doi: 10.2741/goldberg.

Lipoprotein lipase: physiology, biochemistry, and molecular biology

I J Goldberg  1 , M Merkel
Affiliations
Review

Lipoprotein lipase: physiology, biochemistry, and molecular biology

I J Goldberg et al. Front Biosci. .

Abstract

Lipoprotein lipase (LpL) is the primary enzyme responsible for conversion of lipoprotein triglyceride into free fatty acids and monoglyderides. This permits their uptake into muscle and adipose. The roles of this enzyme in normal and altered physiology are reviewed. In addition, the relationship of LpL activity and genetic variations of LpL and human disease are summarized.

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