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Case Reports
. 2001 Mar;39(3):1134-6.
doi: 10.1128/JCM.39.3.1134-1136.2001.

Cutaneous infection caused by Aspergillus ustus, an emerging opportunistic fungus in immunosuppressed patients

J Gené  1 , A Azón-Masoliver, J Guarro, G De Febrer, A Martínez, C Grau, M Ortoneda, F Ballester
Affiliations
Case Reports

Cutaneous infection caused by Aspergillus ustus, an emerging opportunistic fungus in immunosuppressed patients

J Gené et al. J Clin Microbiol. 2001 Mar.

Abstract

We report a case of primary cutaneous infection by the emerging fungus Aspergillus ustus in an immunosuppressed patient after a domestic accident. The patient failed to respond to itraconazole and died before receiving a new treatment with amphotericin B. There have been eight other cases reported since 1973, and only two patients survived the infection. In vitro susceptibility testing of seven antifungal drugs showed that terbinafine and the new azole derivative UR-9825 were the most active against this fungus.

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Figures

FIG. 1
FIG. 1
Erythematous plaque on left forearm and hand, with granulomatous and suppurative borders.
FIG. 2
FIG. 2
(A) Giemsa stain of biopsy tissue from the left forearm showing segmented hyphae. (B and C) Conidiophore, conidia, and Hülle cells of A. ustus, FMR 6729. Bars, 10 (A and C) and 20 (B) μm.
See this image and copyright information in PMC

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