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Case Reports
. 2001 Feb;7(1):38-42.
doi: 10.1097/00054725-200102000-00006.

Infliximab for the treatment of orofacial Crohn's disease

U Mahadevan  1 , W J Sandborn
Affiliations
Case Reports

Infliximab for the treatment of orofacial Crohn's disease

U Mahadevan et al. Inflamm Bowel Dis. 2001 Feb.

Abstract

Orofacial manifestations of Crohn's disease can be difficult to diagnose and treat. We report a case in which the orofacial lesions occurred 7 years prior to the diagnosis of underlying inflammatory bowel disease. The patient was refractory to mesalamine and systemic corticosteroids but responded to infliximab, the chimeric monoclonal antibody to tumor necrosis factor (TNF-alpha). A review of the literature of the orofacial granulomatoses is presented as well.

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