Running on Ran: nuclear transport and the mitotic spindle

M Dasso¹

Affiliations

Free article

Review

M Dasso. Cell. 2001.

Free article

. 2001 Feb 9;104(3):321-4.

doi: 10.1016/s0092-8674(01)00218-5.

M Dasso¹

¹ Laboratory of Gene Regulation and Development, NICHD/NIH, Building 18, Room 106, 18 Library Drive MSC-5431, Bethesda, MD 20892, USA.

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Comment on

Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity.
Gruss OJ, Carazo-Salas RE, Schatz CA, Guarguaglini G, Kast J, Wilm M, Le Bot N, Vernos I, Karsenti E, Mattaj IW. Gruss OJ, et al. Cell. 2001 Jan 12;104(1):83-93. doi: 10.1016/s0092-8674(01)00193-3. Cell. 2001. PMID: 11163242
Importin beta is a mitotic target of the small GTPase Ran in spindle assembly.
Nachury MV, Maresca TJ, Salmon WC, Waterman-Storer CM, Heald R, Weis K. Nachury MV, et al. Cell. 2001 Jan 12;104(1):95-106. doi: 10.1016/s0092-8674(01)00194-5. Cell. 2001. PMID: 11163243