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. 1975 Jan;83(1):127-30.
doi: 10.1111/j.1699-0463.1975.tb01364.x.

Atypical germ cells in the adjacent "normal" tissue of testicular tumours

N E Skakkebaek

Atypical germ cells in the adjacent "normal" tissue of testicular tumours

N E Skakkebaek. Acta Pathol Microbiol Scand A. 1975 Jan.

Abstract

Recently a possible intratubular carcinoma-in-situ of the human testis was described. The same histological picture has been found in the residual testicular tissue in 17 out of 22 men with either seminoma, embryonal carcinoma or terato-carcinoma. The hypothesis is put forward that the described cells may represent malignant germ cells from which testicular germ cell tumours of different types may originate.

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