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Case Reports
. 2001 Feb;13(2):191-2.
doi: 10.1097/00042737-200102000-00016.

Infliximab therapy for Crohn's disease in the presence of chronic hepatitis C infection

S Campbell  1 , S Ghosh
Affiliations
Case Reports

Infliximab therapy for Crohn's disease in the presence of chronic hepatitis C infection

S Campbell et al. Eur J Gastroenterol Hepatol. 2001 Feb.

Abstract

Treatment of Crohn's disease with infliximab is an important drug therapy for patients with refractory and fistulating disease. There are concerns over its use in a proportion of Crohn's patients with concurrent hepatitis C infection, since there are theoretical risks of accelerated hepatic decompensation due to the immunomodulatory impact of infliximab. We report a patient with both Crohn's disease and ongoing active hepatitis C infection who underwent infliximab therapy, with no worsening of his liver function or PCR status.

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