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Review
. 2001 Mar 9;492(1-2):4-8.
doi: 10.1016/s0014-5793(01)02198-6.

Pathophysiological relevance of mitochondria in NAD(+) metabolism

F Di Lisa  1 , M Ziegler
Affiliations
Free article
Review

Pathophysiological relevance of mitochondria in NAD(+) metabolism

F Di Lisa et al. FEBS Lett. .
Free article

Abstract

Pyridine nucleotides are mostly stored within mitochondria where they are involved in different functions ranging from energy metabolism to cellular signaling. Here we discuss the mechanisms of mitochondrial NAD(+) metabolism and release that may contribute to the crucial roles played by these organelles as triggers or amplifiers of physiological and pathological events.

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