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Review
. 2000 Dec;1(3):187-98.
doi: 10.1038/35043117.

Three ways to make a vesicle

T Kirchhausen  1
Affiliations
Review

Three ways to make a vesicle

T Kirchhausen. Nat Rev Mol Cell Biol. 2000 Dec.

Erratum in

  • Nat Rev Mol Cell Biol 2001 Mar;2(3):216

Abstract

Cargo molecules have to be included in carrier vesicles of different forms and sizes to be transported between organelles. During this process, a limited set of proteins, including the coat proteins COPI, COPII and clathrin, carries out a programmed set of sequential interactions that lead to the budding of vesicles. A general model to explain the formation of coated vesicles is starting to emerge but the picture is more complex than we had imagined.

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