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Review
. 2001 Jan;2(1):33-8.
doi: 10.1038/35047605.

Ancient origin of the Hox gene cluster

Affiliations
Review

Ancient origin of the Hox gene cluster

D E Ferrier et al. Nat Rev Genet. 2001 Jan.

Abstract

The Hox gene cluster has a crucial function in body patterning during animal development. How and when this gene cluster originated is being clarified by recent data from Cnidaria, a basal animal phylum. The characterization of Hox-like genes from Hydra, sea anemones and jellyfish has revealed that a Hox gene cluster is extremely ancient, having originated even before the divergence of these basal animals.

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