Review
doi: 10.1001/archneur.58.3.360.
Age-related memory decline: current concepts and future directions
Affiliations
- PMID: 11255438
- DOI: 10.1001/archneur.58.3.360
Item in Clipboard
Review
Age-related memory decline: current concepts and future directions
Arch Neurol.
2001 Mar.
Abstract
The effect of age on memory and the brain has been the focus of many studies. Results have identified critical questions that need to be addressed to further our understanding of age-related memory decline: Is cognitive decline diffuse or selective? Where does memory decline localize to anatomically? Does decline represent an abnormal state? What are the causes of memory decline? What level of analysis is needed to investigate age-related cortical changes? These questions are reviewed herein, and attempts at early answers are discussed.
Similar articles
-
Memory in old age: patterns of decline and preservation.Semin Speech Lang. 2001;22(2):117-25. doi: 10.1055/s-2001-13936. Semin Speech Lang. 2001. PMID: 11373066 Review.
-
Reward-based decision-making and aging.Brain Res Bull. 2005 Nov 15;67(5):382-90. doi: 10.1016/j.brainresbull.2005.06.010. Epub 2005 Jul 11. Brain Res Bull. 2005. PMID: 16216684 Review.
-
Changes in hippocampal volume and neuron number co-occur with memory decline in old homing pigeons (Columba livia).Neurobiol Learn Mem. 2016 May;131:117-20. doi: 10.1016/j.nlm.2016.03.014. Epub 2016 Mar 18. Neurobiol Learn Mem. 2016. PMID: 27003117
-
Insights into the ageing mind: a view from cognitive neuroscience.Nat Rev Neurosci. 2004 Feb;5(2):87-96. doi: 10.1038/nrn1323. Nat Rev Neurosci. 2004. PMID: 14735112 Review. No abstract available.
-
Reversing age-related decline in working memory.Rejuvenation Res. 2011 Oct;14(5):557-9. doi: 10.1089/rej.2011.1247. Rejuvenation Res. 2011. PMID: 22013901 Review.
Cited by
-
Isolating pathogenic mechanisms embedded within the hippocampal circuit through regional vulnerability.Neuron. 2014 Oct 1;84(1):32-39. doi: 10.1016/j.neuron.2014.08.030. Neuron. 2014. PMID: 25277453 Free PMC article. Review.
-
Sensory capability and information integration independently explain the cognitive status of healthy older adults.Sci Rep. 2020 Dec 31;10(1):22437. doi: 10.1038/s41598-020-80069-8. Sci Rep. 2020. PMID: 33384454 Free PMC article.
-
Pinpointing synaptic loss caused by Alzheimer's disease with fMRI.Behav Neurol. 2009;21(1):93-100. doi: 10.3233/BEN-2009-0240. Behav Neurol. 2009. PMID: 19847048 Free PMC article. Review.
-
Longitudinal association between changes in resting-state network connectivity and cognition trajectories: The moderation role of a healthy diet.Front Hum Neurosci. 2023 Jan 19;16:1043423. doi: 10.3389/fnhum.2022.1043423. eCollection 2022. Front Hum Neurosci. 2023. PMID: 36741777 Free PMC article.
-
Functional Connectivity of Hippocampal CA3 Predicts Neurocognitive Aging via CA1-Frontal Circuit.Cereb Cortex. 2020 Jun 30;30(8):4297-4305. doi: 10.1093/cercor/bhaa008. Cereb Cortex. 2020. PMID: 32239141 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical
