Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2001 Apr;45(4):1295-7.
doi: 10.1128/AAC.45.4.1295-1297.2001.

In vitro activities of linezolid against multiple Nocardia species

Affiliations

In vitro activities of linezolid against multiple Nocardia species

B A Brown-Elliott et al. Antimicrob Agents Chemother. 2001 Apr.

Abstract

Linezolid was tested by broth microdilution against 140 clinical Nocardia isolates belonging to seven species. The MIC at which 50% of the strains are inhibited (MIC50) and MIC90 for all species other than Nocardia farcinica were 2 and 4 microg/ml. Linezolid is the first antimicrobial agent demonstrated to be active against all Nocardia species.

PubMed Disclaimer

References

    1. Bach M C, Monaco A P, Finland M. Pulmonary nocardiosis: therapy with minocycline and with erythromycin plus ampicillin. JAMA. 1973;224:1378–1381. - PubMed
    1. Biehle J R, Cavalieri S J, Saubolle M A, Getsinger L J. Comparative evaluation of the E test for susceptibility testing of Nocardia species. Diagn Microbiol Infect Dis. 1994;19:101–110. - PubMed
    1. Bowersock T L, Salmon S A, Portis E S, Prescott J F, Robison D A, Ford C W, Watts J L. MICs of oxazolidinones for Rhodococcus equi strains isolated from humans and animals. Antimicrob Agents Chemother. 2000;44:1367–1369. - PMC - PubMed
    1. Brown B A, Wallace R J., Jr . Broth microdilution MIC test for Nocardia spp. In: Isenberg H D, editor. Clinical microbiology procedures handbook. Washington, D.C.: American Society for Microbiology; 1992. p. 5.12.1.
    1. Cynamon M H, Klemens S P, Sharpe C A, Chase S. Activities of several novel oxazolidinones against Mycobacterium tuberculosisin a murine model. Antimicrob Agents Chemother. 1999;43:1189–1191. - PMC - PubMed

Publication types