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. 2001 Feb;2(2):91-5.
doi: 10.1093/embo-reports/kve029.

The 'double lives' of membrane lipids. Workshop: Anno 2000. A lipid milestone

J A Killian  1 , G van Meer
Affiliations

The 'double lives' of membrane lipids. Workshop: Anno 2000. A lipid milestone

J A Killian et al. EMBO Rep. 2001 Feb.
No abstract available

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Figures

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Fig. 1. Monolayer set-up as used by Gorter and Grendel (1925). A lipid extract of erythrocytes was spread at the lipid–water interface in a Langmuir trough, after which the lipids were compressed by a floating barrier. The point at which the surface layer offered resistance was interpreted as the point at which a closely packed monolayer was formed. This area was twice the calculated surface area of the erythrocytes from which the lipids had been extracted, which led to the first lipid bilayer model.
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Fig. 2. Sphingolipid/cholesterol rafts make thick membranes. A domain (orange) of tall sphingolipids (long thin green barrels) and cholesterol (short green barrel) surrounded by stocky unsaturated PC (thick green barrels in blue environment) in the outer monolayer, potentially complemented by phosphatidylserine/cholesterol rafts (yellow) in PE (green) on the cytosolic side of a mammalian plasma membrane. The depicted domain contains ∼700 lipid molecules in each leaflet and has a thickness of ∼50 Å versus a thickness of ∼40 Å for the bulk membrane.
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The authors* and organizers+ from left to right are: J.A.F. Op den Kamp+ and B. de Kruijff, G. van Meer* and J.A. Killian*.
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The Anno 2000 membrane lipid workshop was organized by J.A.F. Op den Kamp and B. de Kruijff, and was held at Utrecht University (Utrecht, The Netherlands) October 26–28, 2000.
See this image and copyright information in PMC

References

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    1. Gorter E. and Grendel, J. (1925) On bimolecular layers of lipoids on the chromocytes of blood. J. Exp. Med., 41, 439–443. - PMC - PubMed
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