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. 2001 Mar;8(2):170-4.
doi: 10.1007/s10434-001-0170-x.

Lymph node micrometastases in patients with early gastric cancer: experience with 139 patients

P Morgagni  1 , L Saragoni, S Folli, M Gaudio, E Scarpi, F Bazzocchi, G A Marra, A Vio
Affiliations

Lymph node micrometastases in patients with early gastric cancer: experience with 139 patients

P Morgagni et al. Ann Surg Oncol. 2001 Mar.

Abstract

Background: Although lymph node metastases in patients with early gastric cancer (EGC) is an important prognostic factor, the prognostic relevance of lymph node micrometastases is still uncertain.

Methods: The authors studied 1488 lymph nodes, which were histologically confirmed as pN0, dissected from 139 patients who were treated for EGC between 1976-1994. Micrometastases were defined as a single or small cluster of neoplastic cells identifiable only by immunohistochemical methods.

Results: Lymph node micrometastases was observed in 24 of the 139 patients (17%). No significant correlation was observed between micrometastases and other clinicopathological characteristics. Analysis of overall survival showed no significant difference between the micrometastases positive and negative groups.

Conclusion: The results of our study show that the presence of lymph node micrometastases in EGC does not have an influence on patient prognosis.

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