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Comment
. 2001 Mar 27;98(7):3625-7.
doi: 10.1073/pnas.071051998. Epub 2001 Mar 20.

The GABAergic reticular nucleus: a preferential target of corticothalamic projections

M Steriade  1
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Comment

The GABAergic reticular nucleus: a preferential target of corticothalamic projections

M Steriade. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Functional relations between corticothalamic, thalamic reticular (RE), and thalamocortical (TC) neurons. (A) Three neurons (cortical, RE, and TC) were intracellularly recorded and stained in cats. Signs of excitation and inhibition are indicated by plus and minus. For the sake of simplicity, local-circuit inhibitory neurons in cortex and thalamus are not illustrated. (Insets) The response of RE and TC neurons to cortical stimulation (arrowheads point to stimulus artifacts). The GABAergic RE neuron responded to cortical stimulation with a high-frequency spike-burst, followed by a sequence of spindle waves on a depolarizing envelope (membrane potential, −68 mV). The TC neuron responded to cortical stimulation (arrowhead) with a biphasic IPSP, leading to a low-threshold spike (LTS) and a sequence of hyperpolarizing spindle waves (membrane potential, −70 mV). (B) Relations between cortical (area 4), RE, and TC neurons of cat during spontaneously occurring, cortically generated seizure with polyspike-wave (PSW) complexes at 2 Hz. Note IPSPs in TC neuron (filled circles) in close time relation with spike-bursts fired by RE neuron, driven from cortex. Recordings are modified from refs. and .
See this image and copyright information in PMC

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References

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