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. 1975 May 16;100(20):1135-8.

[Inhibition by somatostatin of pancreatic juice and enzyme secretion and gallbladder contraction in man induced by secretin and cholecystokinin-pancreozymin administration (author's transl)]

[Article in German]
  • PMID: 1126301

[Inhibition by somatostatin of pancreatic juice and enzyme secretion and gallbladder contraction in man induced by secretin and cholecystokinin-pancreozymin administration (author's transl)]

[Article in German]
W Creutzfeldt et al. Dtsch Med Wochenschr. .

Abstract

Somatostatin (200 mug/h) was administered to five healthy volunteers after submaximal stimulation of exocrine pancreatic secretion with 0.33 KU secretin or cholecystokinin-pancreozymin, given intravenously. In all instances there was a significant reduction in duodenal secretory volume after secretin, without any change in HCO3- concentration. Stimulation of enzyme secretion by cholecystokinin-pancreozymin was significantly inhibited and gallbladder contraction abolished.

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