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. 2000;51(3):137-42.

[Synthesis of 3-carbethoxi-2-phenyl-4-quinolones. Potential antimitotics]

[Article in Spanish]
T Quintero  1 , E Pernía, W J Guzmán, C J Márquez
Affiliations
  • PMID: 11265447

[Synthesis of 3-carbethoxi-2-phenyl-4-quinolones. Potential antimitotics]

[Article in Spanish]
T Quintero et al. Acta Cient Venez. 2000.

Abstract

The synthesis of the title compounds involved four main reactions: condensation between the acid chlorides and diethyl malonate to obtain the diethyl benzoylmalonates; transformation of these in diethyl chloroarylidenmalonates; the reaction of the substituted anilines with the chlorinated compounds and finally the thermal cyclization in diphenyl ether.

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