Identification and characterization of a gene encoding a 35-kDa protein from Mycobacterium avium subspecies paratuberculosis
- PMID: 11267779
- DOI: 10.1111/j.1574-6968.2001.tb10564.x
Identification and characterization of a gene encoding a 35-kDa protein from Mycobacterium avium subspecies paratuberculosis
Abstract
Mycobacterium avium subspecies paratuberculosis is the causative agent of Johne's disease, a chronic enteritis in ruminants. A gene homologous to that of 35-kDa antigen of Mycobacterium leprae was cloned and sequenced from Mycobacterium paratuberculosis. The database searches revealed 82.79% and 95.67% similarities of its nucleotide sequence, with those of immunodominant 35-kDa protein of M. leprae and M. avium, respectively.
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