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Case Reports
. 2001 Feb 10;357(9254):442.
doi: 10.1016/S0140-6736(00)04011-3.

Herpes simplex virus 1 transmission through corneal transplantation

L Remeijer, J Maertzdorf, P Doornenbal, G M Verjans, A D Osterhaus
Case Reports

Herpes simplex virus 1 transmission through corneal transplantation

L Remeijer et al. Lancet. .

Abstract

Genetic characterisation of herpes simplex virus type 1 (HSV-1) DNA isolated from a donor cornea before and after corneal transplantation demonstrated the transmission of HSV-1 through transplantation. This study is the first to provide conclusive evidence for the transmission of HSV-1 by penetrating keratoplasty with subsequent reactivation of donor-derived HSV-1 in the transplanted cornea.

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