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Comparative Study
. 1975 May 1;141(5):935-43.
doi: 10.1084/jem.141.5.935.

Association of HL-A 5 and immune responsiveness in vitro to streptococcal antigens

L J Greenberg, E D Gray, E J Yunis
Comparative Study

Association of HL-A 5 and immune responsiveness in vitro to streptococcal antigens

L J Greenberg et al. J Exp Med. .

Abstract

Lymphocytes, from randomly selected individuals having normal immune function, when incubated in vitro with varying concentrations of streptococcal antigens, responded in three ways: (a) response over the entire antigen concentration range, i.e., responders; (b) low response to only the highest antigen concentrations; and (c) no response at any antigen concentration. Frequency distribution analysis of these groups indicated that a significant association occurred between the ability to respond and HL-A 5.

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