Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2001;2(3):REVIEWS1009.
doi: 10.1186/gb-2001-2-3-reviews1009. Epub 2001 Mar 5.

Fungal virulence studies come of age

Affiliations
Review

Fungal virulence studies come of age

F C Odds et al. Genome Biol. 2001.

Abstract

Sophisticated molecular biological research has revealed many virulence attributes in at least four pathogenic fungi, but the future study of fungal virulence requires investigators to distinguish between molecules that directly interact with the host, molecules that regulate these, and molecules that are always required for fungal growth and survival, independent of the host.

PubMed Disclaimer

References

    1. Colonna-Romano S, Porta A, Franco A, Kobayashi GS, Maresca B. Identification and isolation by DDRT-PCR of genes differentially expressed by Histoplasma capsulatum during macrophages infection. Microb Pathog. 1998;25:55–66. - PubMed
    1. Sebghati TS, Engle JT, Goldman WE. Intracellular parasitism by Histoplasma capsulatum: fungal virulence and calcium dependence. Science. 2000;290:1368–1372. doi: 10.1126/science.290.5495.1368. - DOI - PubMed
    1. Retallack DM, Heinecke EL, Gibbons R, Deepe GS, Woods JP. The URA5 gene is necessary for Histoplasma capsulatum growth during infection of mouse and human cells. Infect Immun. 1999;67:624–629. - PMC - PubMed
    1. Retallack DM, Deepe GS, Woods JP. Applying in vivo expression technology (IVET) to the fungal pathogen Histoplasma capsulatum. Microb Pathog. 2000;28:169–182. - PubMed
    1. Fonzi W, Irwin M. Isogenic strain construction and gene mapping in Candida albicans. Genetics. 1993;134:717–728. - PMC - PubMed