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Comment
. 2001 Apr;117(4):361-6.
doi: 10.1085/jgp.117.4.361.

Transduction gain in light adaptation of rod photoreceptors

Comment

Transduction gain in light adaptation of rod photoreceptors

D R Pepperberg. J Gen Physiol. 2001 Apr.
No abstract available

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Figures

Figure 1
Figure 1
Photocurrent flash responses reproduced from Fig. 2 of the study by Nikonov et al. 2000. Flash strengths used to obtain each family of responses were as follows: (in estimated Φ per flash) 260, 830, 2,600, 8,300, 26,000, 83,000 and 260, 000. (A–C) Dark-adapted responses compared with responses obtained with backgrounds of 260 (A), 810 (B), and 2,600 (C) Φ s−1. In each panel, the data obtained in background light have been vertically shifted as a group to achieve a visual match of dark- and light-adapted saturating amplitudes. (D–F) Similar comparison of responses obtained with differing backgrounds. D and E compare responses obtained at 260 Φ s−1 with those obtained at 810 (D) and 2,600 Φ s−1 (E). F compares responses obtained at 810 Φ s−1 with those obtained at 2,600 Φ s−1. Data reproduced by scanning the published Fig. 2 of Nikonov et al. 2000 and reformatting the data in Adobe Photoshop. Illustrated vertical axes (pA) in A–F are those relevant to the dark-adapted data (A–C), the data obtained at 260 Φ s−1 (D and E), and the data obtained at 810 Φ s−1 (F). See text for further details.

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References

    1. Nikonov S., Lamb T.D., Pugh E.N., Jr. The role of steady phosphodiesterase activity in the kinetics and sensitivity of the light-adapted salamander rod photoresponse. J. Gen. Physiol. 2000;116:795–824. - PMC - PubMed
    1. Pepperberg D.R. Does rod phototransduction involve the delayed transition of activated rhodopsin to a second, more active catalytic state? Vis. Neurosci. 1998;15:1067–1078. - PubMed
    1. Pepperberg D.R., Jin J., Jones G.J. Modulation of transduction gain in light adaptation of retinal rods. Vis. Neurosci. 1994;11:53–62. - PubMed
    1. Torre V., Matthews H.R., Lamb T.D. Role of calcium in regulating the cyclic GMP cascade of phototransduction in retinal rods. Proc. Natl. Acad. Sci. USA. 1986;83:7109–7113. - PMC - PubMed

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