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Comment
. 2001 Apr;117(4):361-6.
doi: 10.1085/jgp.117.4.361.

Transduction gain in light adaptation of rod photoreceptors

D R Pepperberg
Comment

Transduction gain in light adaptation of rod photoreceptors

D R Pepperberg. J Gen Physiol. 2001 Apr.
No abstract available

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Figures

Figure 1
Figure 1
Photocurrent flash responses reproduced from Fig. 2 of the study by Nikonov et al. 2000. Flash strengths used to obtain each family of responses were as follows: (in estimated Φ per flash) 260, 830, 2,600, 8,300, 26,000, 83,000 and 260, 000. (A–C) Dark-adapted responses compared with responses obtained with backgrounds of 260 (A), 810 (B), and 2,600 (C) Φ s−1. In each panel, the data obtained in background light have been vertically shifted as a group to achieve a visual match of dark- and light-adapted saturating amplitudes. (D–F) Similar comparison of responses obtained with differing backgrounds. D and E compare responses obtained at 260 Φ s−1 with those obtained at 810 (D) and 2,600 Φ s−1 (E). F compares responses obtained at 810 Φ s−1 with those obtained at 2,600 Φ s−1. Data reproduced by scanning the published Fig. 2 of Nikonov et al. 2000 and reformatting the data in Adobe Photoshop. Illustrated vertical axes (pA) in A–F are those relevant to the dark-adapted data (A–C), the data obtained at 260 Φ s−1 (D and E), and the data obtained at 810 Φ s−1 (F). See text for further details.
See this image and copyright information in PMC

Comment on

References

    1. Nikonov S., Lamb T.D., Pugh E.N., Jr. The role of steady phosphodiesterase activity in the kinetics and sensitivity of the light-adapted salamander rod photoresponse. J. Gen. Physiol. 2000;116:795–824. - PMC - PubMed
    1. Pepperberg D.R. Does rod phototransduction involve the delayed transition of activated rhodopsin to a second, more active catalytic state? Vis. Neurosci. 1998;15:1067–1078. - PubMed
    1. Pepperberg D.R., Jin J., Jones G.J. Modulation of transduction gain in light adaptation of retinal rods. Vis. Neurosci. 1994;11:53–62. - PubMed
    1. Torre V., Matthews H.R., Lamb T.D. Role of calcium in regulating the cyclic GMP cascade of phototransduction in retinal rods. Proc. Natl. Acad. Sci. USA. 1986;83:7109–7113. - PMC - PubMed

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