Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci
- PMID: 11279517
- DOI: 10.1038/86867
Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci
Abstract
We have carried out a genome screen for atopic dermatitis (AD) and have identified linkage to AD on chromosomes 1q21, 17q25 and 20p. These regions correspond closely with known psoriasis loci, as does a previously identified AD locus on chromosome 3q21. The results indicate that AD is influenced by genes with general effects on dermal inflammation and immunity.
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