Steroid receptors and metastatic potential in endometrial cancers
- PMID: 11282273
- DOI: 10.1016/s0960-0760(00)00176-x
Steroid receptors and metastatic potential in endometrial cancers
Abstract
The relative overexpression of estrogen receptor (ER)-alpha exon 5 splicing variant, the disrupted synchronization of ER-beta and ER-alpha expressions, and the suppression of progesterone receptor (PR) form A expression as a transcriptional repressor might be related to metastatic potential of uterine endometrial cancers, leading to poor patient prognosis related to estrogen refractoriness.
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