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Review
. 2000 Dec 31;75(4-5):209-12.
doi: 10.1016/s0960-0760(00)00176-x.

Steroid receptors and metastatic potential in endometrial cancers

J Fujimoto  1 , H Sakaguchi, I Aoki, S Khatun, H Toyoki, T Tamaya
Affiliations
Review

Steroid receptors and metastatic potential in endometrial cancers

J Fujimoto et al. J Steroid Biochem Mol Biol. .

Abstract

The relative overexpression of estrogen receptor (ER)-alpha exon 5 splicing variant, the disrupted synchronization of ER-beta and ER-alpha expressions, and the suppression of progesterone receptor (PR) form A expression as a transcriptional repressor might be related to metastatic potential of uterine endometrial cancers, leading to poor patient prognosis related to estrogen refractoriness.

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