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Comment
. 2001 Apr 2;193(7):F27-30.
doi: 10.1084/jem.193.7.f27.

V(D)J recombination becomes accessible

M S Krangel  1
Affiliations
Comment

V(D)J recombination becomes accessible

M S Krangel. J Exp Med. .
No abstract available

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Figure 1
Figure 1
Possible mechanisms by which histone acetylation may be regulated at a prototypical TCR/Ig locus. (a) Low-level, domain-wide acetylation associated with locus repositioning in the nucleus; (b) localized acetylation targeted to enhancers and promoters by the assembly of transcriptional activators and coactivators; (c) acetylation extending across transcription units as a consequence of transcriptional elongation. Arrows denote transcriptional promoters, open rectangles denote gene segments (V, D, J, and C), an open oval denotes a transcriptional enhancer (E), and filled triangles denote RSSs.
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References

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