Comment on

• Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie.

  Mabbott NA, Bruce ME, Botto M, Walport MJ, Pepys MB. Mabbott NA, et al. Nat Med. 2001 Apr;7(4):485-7. doi: 10.1038/86562. Nat Med. 2001. PMID: 11283677
• Complement facilitates early prion pathogenesis.

  Klein MA, Kaeser PS, Schwarz P, Weyd H, Xenarios I, Zinkernagel RM, Carroll MC, Verbeek JS, Botto M, Walport MJ, Molina H, Kalinke U, Acha-Orbea H, Aguzzi A. Klein MA, et al. Nat Med. 2001 Apr;7(4):488-92. doi: 10.1038/86567. Nat Med. 2001. PMID: 11283678