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Review
. 2001 Apr 1;197(1):11-8.
doi: 10.1111/j.1574-6968.2001.tb10575.x.

Cytotoxic T cells and mycobacteria

C L Silva  1 , V L Bonato, K M Lima, A A Coelho-Castelo, L H Faccioli, A Sartori, A O De Souza, S C Leão
Affiliations
Review

Cytotoxic T cells and mycobacteria

C L Silva et al. FEMS Microbiol Lett. .

Abstract

How the immune system kills Mycobacterium tuberculosis is still a puzzle. The classical picture of killing due to phagocytosis by activated macrophages may be only partly correct. Based on recent evidence, we express here the view that cytotoxic T lymphocytes also make an important contribution and suggest that DNA vaccines might be a good way to enhance this.

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