Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2001 Mar;24(3):247-52.
doi: 10.1002/clc.4960240314.

Magnetic resonance imaging of old myocardial infarction in young patients with a history of Kawasaki disease

M Fujiwara  1 , T N Yamada, Y Ono, M Yoshibayashi, T Kamiya, S Furukawa
Affiliations
Case Reports

Magnetic resonance imaging of old myocardial infarction in young patients with a history of Kawasaki disease

M Fujiwara et al. Clin Cardiol. 2001 Mar.

Abstract

Background: On magnetic resonance imaging (MRI) using gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA) as contrast medium, images of infarct regions are enhanced in acute myocardial infarction (AMI). In old myocardial infarction (OMI), thinning of the myocardial walls is present, but images are no longer enhanced by Gd-DTPA. On the other hand, MI in children with a history of Kawasaki disease (KD), several differences from adult MI are observed.

Hypothesis: The aim of this study was to evaluate the lesions that result from OMI in children with a history of KD using MRI with Gd-DTPA as a contrast medium.

Methods: The subjects were 16 young patients with a history of KD who were diagnosed as having OMI. Of these, both thinning of the myocardial wall and MRI enhancement by Gd-DTPA were observed in 4 cases, thinning alone was observed in 6 cases, Gd-DTPA image enhancement alone was observed in 3 cases, and neither thinning nor Gd-DTPA image enhancement was observed in 3 cases.

Results: The Gd-DTPA-image-enhanced, OMI-induced lesions observed in patients with KD were different from those observed in adults; this might be attributable to histologic differences.

Conclusion: Magnetic resonance imaging using Gd-DTPA can evaluate myocardial thinning and presence of circulation noninvasively at the same time and is considered to be useful for long-term follow up of the patients with KD and OMI.

PubMed Disclaimer

References

    1. Weinmann HJ, Brasch RC, Press WR, Wesbey GE: Characteristics of gadolinium‐DTPA complex: A potential NMR contrast agent. Am J Roentgenol 1984; 142: 619–624 - PubMed
    1. Schaefer S, Malloy CR, Katz J, Parkey RW, Buja LM, Willerson JT, Peshock RM: Gadolinium‐DTPA‐enhanced nuclear magnetic resonance imaging of reperfusion myocardium: Identification of the myocardial bed at risk. J Am Coll Cardiol 1988; 12: 1064–1072 - PubMed
    1. Van Dijkman PR, van der Wall EE, de Roos A, Matheijssen NA, van Rossum AC, Doombos J, van der Laarse A, van Voorthuisen AE, Bruschke AV: Acute, subacute, and chronic myocardial infarction: Quantitative analysis of gadolinium‐enhanced MR images. Radiology 1991; 180: 147–151 - PubMed
    1. Nishimura T, Kobayashi H, Ohara Y, Yamada N, Haze K, Takamiya M, Hiramori K: Serial assessment of myocardial infarction by using gated MR imaging and Gd‐DTPA. Am J Roentgenol 1989; 153: 715–720 - PubMed
    1. Kawasaki T, Kosaki F, Okawa S, Shigematsu I, Yanagawa H: A new infantile acute febric mucocutaneous lymph node syndrome (MLNS) prevailing in Japan. Pediatrics 1974; 54: 271–276 - PubMed

Publication types