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. 2001 Apr 2;86(14):3192-5.
doi: 10.1103/PhysRevLett.86.3192.

Dynamic concentration of motors in microtubule arrays

F Nédélec  1 , T Surrey, A C Maggs
Affiliations

Dynamic concentration of motors in microtubule arrays

F Nédélec et al. Phys Rev Lett. .

Abstract

We present experimental and theoretical studies of the dynamics of molecular motors in microtubule arrays and asters. By solving a convection-diffusion equation we find that the density profile of motors in a two-dimensional aster is characterized by continuously varying exponents. Simulations are used to verify the assumptions of the continuum model. We observe the concentration profiles of kinesin moving in quasi-two-dimensional artificial asters by fluorescent microscopy and compare with our theoretical results.

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