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. 1979 Jul;16(1):104-5.
doi: 10.1128/AAC.16.1.104.

Isoniazid inhibition of the synthesis of monounsaturated long-chain fatty acids in Mycobacterium tuberculosis H37Ra

L A Davidson, K Takayama

Isoniazid inhibition of the synthesis of monounsaturated long-chain fatty acids in Mycobacterium tuberculosis H37Ra

L A Davidson et al. Antimicrob Agents Chemother. 1979 Jul.

Abstract

Isoniazid inhibited C(24) and C(26) monounsaturated fatty acid synthesis in Mycobacterium tuberculosis H37Ra. Time courses of this inhibition and that of mycolic acid synthesis were similar.

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References

    1. Lipids. 1978 Sep;13(9):575-9 - PubMed
    1. Mol Cell Biochem. 1975 May 30;7(2):87-104 - PubMed
    1. Antimicrob Agents Chemother. 1972 Jul;2(1):29-35 - PubMed
    1. Ann N Y Acad Sci. 1974 May 10;235(0):426-38 - PubMed
    1. Biochim Biophys Acta. 1968 Apr 16;158(1):130-43 - PubMed

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