Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Jun 1;179(3):483-7.
doi: 10.1042/bj1790483.

Strain differences in rat liver (UDP-glucuronyltransferase activity towards androsterone

M Matsui, F Nagai, S Aoyagi

Strain differences in rat liver (UDP-glucuronyltransferase activity towards androsterone

M Matsui et al. Biochem J. .

Abstract

Male Donryu, Wistar King rats showed discontinuous variations in hepatic microsomal UDP-glucuronyltransferase activities towards androsterone, but not towards testosterone, bilirubin, phenolphthalein and 4-nitrophenol. Fresh microsomal fraction with a low transferase activity towards androsterone formed 0.049--0.080 nmole of glucuronide/min per mg of protein, whereas fresh microsomal fraction with a high transferase activity towards androsterone formed 0.335--0.557 nmol of glucuronide/min per mg of protein. The microsomal fraction with low enzyme activity towards androsterone was not stimulated by treatment with Triton X-100 or freezing and thawing. In contrast, male Long Evans and Sprague-Dawley rats did not exhibit such diversity.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Biochem J. 1978 Sep 1;173(3):749-57 - PubMed
    1. Biochem J. 1978 Aug 15;174(2):485-9 - PubMed
    1. Biochem Pharmacol. 1979;28(3):411-5 - PubMed
    1. J Biol Chem. 1951 Nov;193(1):265-75 - PubMed
    1. J Steroid Biochem. 1977 Mar;8(3):235-41 - PubMed