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Review
. 2001;3(1):22-7.
doi: 10.1186/bcr266.

Application of magnetic resonance imaging to angiogenesis in breast cancer

Affiliations
Review

Application of magnetic resonance imaging to angiogenesis in breast cancer

M O Leach. Breast Cancer Res. 2001.

Abstract

Magnetic resonance imaging (MRI) techniques enable vascular function to be mapped with high spatial resolution. Current methods for imaging in breast cancer are described, and a review of recent studies that compared dynamic contrast-enhanced MRI with histopathological indicators of tumour vascular status is provided. These studies show correlation between in vivo dynamic contrast measurements and in vitro histopathology. Dynamic contrast-enhanced MRI is also being applied to assessment of the response of breast tumours to treatment.

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Figures

Figure 1
Figure 1
A T1-weighted postcontrast image from a three-dimensional fat-suppressed sequence, showing distinctive rim enhancement. Reprinted from Magn Reson Imaging, volume 18, Brown et al, Magnetic resonance imaging screening in women at genetic risk of breast cancer: imaging and analysis protocol for the UK multicentre study, pp 765-776. Copyright 2000, with permission from Elsevier Science.

References

    1. Folkman J. The role of angiogenesis in tumor growth. Semin Cancer Biol. 1992;3:65–71. - PubMed
    1. Weidner N. Current pathologic methods for measuring intra-tumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res Treat. 1995;36:169–180. - PubMed
    1. Rankin SC. MRI of the breast. Br J Radiol. 2000;73:806–818. - PubMed
    1. Kuhl CK. MRI of breast tumors. Eur Radiol. 2000;10:46–58. - PubMed
    1. Orel SG. MR imaging of the breast. Radiol Clin North Am. 2000;38:899–913. - PubMed

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