Notch pathway: making sense of suppressor of hairless
- PMID: 11301266
- DOI: 10.1016/s0960-9822(01)00109-9
Notch pathway: making sense of suppressor of hairless
Abstract
Suppressor of Hairless (Su(H)) is a DNA-binding protein component of the Notch signalling pathway, thought to be required, with a fragment of the Notch receptor, for target gene activation. Recent studies show that this is only one side of the story: target gene enhancers may be regulated by Su(H) in a variety of different ways.
Comment on
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Notch signaling targets the Wingless responsiveness of a Ubx visceral mesoderm enhancer in Drosophila.Curr Biol. 2001 Mar 20;11(6):375-85. doi: 10.1016/s0960-9822(01)00120-8. Curr Biol. 2001. PMID: 11301248
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