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. 1975 Apr;20(4):359-61.
doi: 10.1007/BF01237793.

Transplantation antigens in Crohn's disease: Linkage of associated ankylosing spondylitis with HL-Aw27

A S Russell, J S Percy, J Schlaut, V E Sartor, J M Goodhart, R W Sherbaniuk, E G Kidd

Transplantation antigens in Crohn's disease: Linkage of associated ankylosing spondylitis with HL-Aw27

A S Russell et al. Am J Dig Dis. 1975 Apr.

Abstract

The complete HL-A antigen profile was examined in 77 patients with Crohn's disease,11 of whom had unequivocal ankylosing spondylitis. There was no significant difference in the frequencies of the HL-A antigens between these 77 patients and 600 normal controls. 10 male patients with Crohn's disease possessed HL-Aw27; all of these had unequivocal ankylosing spondylitis. This antigen may, therefore, be a useful marker of spondylitis in Crohn's disease.

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