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. 2001;92(1-2):122-6.
doi: 10.1159/000056881.

Isolation and initial characterization of the mouse Dnmt3l gene

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Isolation and initial characterization of the mouse Dnmt3l gene

U Aapola et al. Cytogenet Cell Genet. 2001.

Abstract

We have isolated and sequenced the mouse zinc finger gene, Dnmt3l (DNA cytosine-5-methyltransferase 3-like), on mouse chromosome 10, showing similarity to members of the DNMT3/Dnmt3 family. The Dnmt3l protein contains an ADD zinc finger, which Dnmt3l shares with other Dnmt3 family members and Atrx. RT-PCR analysis showed Dnmt3l expression in testis, thymus, ovary, and heart, as well as in 7-day, 15-day, and 17-day mouse embryos.

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