[K-Lymphocyte cytotoxicity: role of human blood group ABO, rhesus and P alloantibodies]
[Article in
French]
- PMID: 113124
Item in Clipboard
[K-Lymphocyte cytotoxicity: role of human blood group ABO, rhesus and P alloantibodies]
[Article in
French]
C R Seances Acad Sci D.
.
Abstract
Using human erythrocytes of known antigenic density, sensitized by ABO and Rhesus (D) alloantibodies, it is shown that K cell cytotoxicity mediated by peripheral blood lymphocytes is directly correlated with the number of IgG molecules specifically bound to the target cell surface. The lytic sensitivity of P1k but not P2 or p erythrocytes coated with anti-Tja (anti-P + P1 + Pk) antibodies, demonstrates that effector K cells are mainly triggered through the IgG ANTI-Pk component of such sera.
Similar articles
-
Lysis of alloantibody-sensitized human erythrocytes by peripheral blood mononuclear cells: heterogeneity of effector populations.J Clin Lab Immunol. 1981 Jan;5(1):41-6. J Clin Lab Immunol. 1981. PMID: 6260947
-
Antibody dependent cellular cytotoxicity (ADCC) against human erythrocytes, mediated by blood group alloantibodies: a model for the role of antigen density in target cell lysis.Z Immunitatsforsch Immunobiol. 1978;154(1):15-33. Z Immunitatsforsch Immunobiol. 1978. PMID: 74918
-
The antibody-dependent cell-mediated cytotoxic (ADCC) reaction. III. Lymphocyte, neutrophil and monocyte cytotoxic activity as a function of the alloantibodies and erythrocyte target cells in the human allogeneic ADCC assay.Clin Invest Med. 1983;6(1):19-24. Clin Invest Med. 1983. PMID: 6831791
-
[Present status of our knowledge on the erythrocyte blood group systems other than ABO and Rh].Rev Fr Transfus. 1969;12(1):Suppl:93-112. Rev Fr Transfus. 1969. PMID: 4989112 Review. French. No abstract available.
-
Macro- and microdifferences in blood group antigens and antibodies.Int Arch Allergy Appl Immunol. 1974;47(4):547-61. doi: 10.1159/000231249. Int Arch Allergy Appl Immunol. 1974. PMID: 4137838 Review. No abstract available.