Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2001;4(1):31-5.
doi: 10.1023/a:1009934412988.

A new model for the origins of chronic disease

D J Barker  1
Affiliations
Review

A new model for the origins of chronic disease

D J Barker. Med Health Care Philos. 2001.

Abstract

Living things are often plastic during their early development and are moulded by the environment. Many human fetuses have to adapt to a limited supply of nutrients, and in doing so they permanently change their physiology and metabolism. These programmed changes may be the origins of a number of diseases in later life, including coronary heart disease, stroke, diabetes and hypertension.

PubMed Disclaimer

Comment in

References

    1. Ann Hum Biol. 1986 Mar-Apr;13(2):143-51 - PubMed
    1. BMJ. 1997 Oct 4;315(7112):837-40 - PubMed
    1. Br J Obstet Gynaecol. 1996 Aug;103(8):814-7 - PubMed
    1. Proc R Soc Lond B Biol Sci. 1974 Jan 22;185(1078):1-17 - PubMed
    1. BMJ. 1995 Jul 15;311(6998):171-4 - PubMed

LinkOut - more resources