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Review
. 2001 Mar;193(3):163-74.
doi: 10.1620/tjem.193.163.

The role of Pax6 in brain patterning

Affiliations
Review

The role of Pax6 in brain patterning

N Osumi. Tohoku J Exp Med. 2001 Mar.

Abstract

Pax6 g ene encodes a transcription factor that plays a pivotal role in various aspects of brain development. Here I review the molecular and cellular mechanisms of how the early brain is patterned, and introduce recent studies on the role of Pax6 in brain patterning, neuronal specification, neuronal migration and axonal extension.

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