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. 1975 Jun;35(6):1453-7.

Identification of phosphorodiamidic acid mustard as a human metabolite of cyclop hosphamide

C Fenselau, M N Kan, S Billets, M Colvin
  • PMID: 1131817

Identification of phosphorodiamidic acid mustard as a human metabolite of cyclop hosphamide

C Fenselau et al. Cancer Res. 1975 Jun.

Abstract

An active metabolite of cyclophosphamide, N,N-bis(2-chloroethyl)phosphorodiamidic acid, has been confirmed as a circulating and excreted metabolite in patients receiving the drug in therapy, by selected ion monitoring on a gas chromatograph mass spectrometer.

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